Ah so many to choose from, I could list a top10 let alone a couple. The fight scene in the bourne ultimatum is pretty darn epic.
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I also really like this fight scene from the korean movie old boy, mainly because of the way it's shot and the music to compliment the scene. Plus if you've seen the movie you know how twisted it all is anyway.
edit: link removed, ^beat me to it
And of course Rocky Balboa vs Ivan Drago - Rocky IV