My top tip: If you are filtering when someone switches lanes in front of you and you realise you are going to hit the driver's door, don't stick your elbow out to protect the bike! Cars are harder than humans...
Serously though, I've experienced Bristol a few times on the bike mate and it's no worse than any other city e.g. Manchester. Just stay very alert and like CG says you will develop a sixth sense for who is about to cut you up.
White lines can cause a noticeable 'shift' (can't think of a better word to describe it) while you're filtering at low speed. The more raised the white lines are and / or the more squared-off your tyres are it seems to have more effect. Best to avoid white lines really, especially in the wet.