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Filipe M.
18-09-06, 03:20 PM
Ahhh the soothing vocal meanderings of Mr D.W. d*ck!!

So is that where your username comes from? And what the hell do you need a script for? :wink:

Jester666
19-09-06, 10:11 AM
It takes lots fo planning and a really complex script to make an SV look as bad as mine! :lol:

Been called Jester for years. From my love of OLD Marillion and my slightly warped sense of humour!! :lol:

Filipe M.
19-09-06, 01:35 PM
It takes lots fo planning and a really complex script to make an SV look as bad as mine! :lol:

Been called Jester for years. From my love of OLD Marillion and my slightly warped sense of humour!! :lol:

:lol:

I'm with you on the old Marillion. Steve Hogarth doesn't have what it takes, IMHO. FACT. :lol:

Tara
19-09-06, 01:39 PM
It takes lots fo planning and a really complex script to make an SV look as bad as mine! :lol:

Been called Jester for years. From my love of OLD Marillion and my slightly warped sense of humour!! :lol:

:lol:

I'm with you on the old Marillion. Steve Hogarth doesn't have what it takes, IMHO. FACT. :lol:
agreed

lynw
20-09-06, 02:17 PM
Back on track before this turns into megathread version 2 :P :wink: :lol:

Dunnet Head is the most northerly point of mainland Scotland not John o' Groats.

John o' Groats is named after Jan de Groot the Dutch mariner who obtained the right to run the ferry service from the mainland to the Orkneys.

The lighthouse at Dunnet Head was built by Robert Louis Stevensons grandfather.

Both are a bloody long way on an SV from Kent but both are well worth the trip provided the weathers good :P :lol: :lol: :lol:

Stingo
20-09-06, 03:50 PM
Admiral Arthur Knyvet Wilson VC CB famously declared that the submarine was "underhand, unfair, and damned UnEnglish." The government, he wrote, should "treat all submarines as pirates in wartime . . . and hang all crews."


Hence submarines fly the Jolly Roger when returning from a war patrol.

The Basket
21-09-06, 09:48 AM
Both are a bloody long way on an SV from Kent but both are well worth the trip provided the weathers good :P :lol: :lol: :lol:

Ouch! :shock:

Steve H
27-09-06, 02:39 PM
90% of people are caused by accidents.

That would explain a lot about the people where I live. :wink:

BernardBikerchick
28-09-06, 09:31 AM
your foot is as big as your arm from your elbow to your wrist !!!!

hovis
28-09-06, 09:52 AM
your foot is as big as your arm from your elbow to your wrist !!!!


i knew that one :wink:

lynw
28-09-06, 12:55 PM
Iva Toguri is the only American convicted of treason to receive a pardon.

her obituary (http://www.telegraph.co.uk/news/main.jhtml?view=DETAILS&grid=&xml=/news/2006/09/28/db2802.xml) makes interesting reading.

hovis
29-09-06, 07:21 AM
26% of all McDonald's employees in Ontario, Canada admit to putting some type of bodily fluid in McDonald's food. :smt078

lynw
01-10-06, 04:26 PM
Flotsam and jetsam actually have different meanings and used to be used independantly of each other.

Flotsam or floatsome were items which were found floating as a consequence of the actions of the sea ie those which came from ships wrecked in storms.

Jetsam refers to items which were thrown overboard by a ships crew.

Lagan is the third term which is hardly ever used these days and it refers to goods and wreckage that sinks to the sea bed.

Mogs
05-10-06, 12:05 PM
I love these old nautical terms, I particularly like “Choc-a-bloc”, which refers to the point at which the two opposing pulleys in a block and tackle system meet and as such have no more room to move.

wyrdness
05-10-06, 12:53 PM
TYPEWRITER is the longest word that can be typed using only one row of the keyboard.

Baph
12-10-06, 10:07 AM
Fuel (95 RON Unleaded) is now 84.9p/litre. Just thought I'd share something that made me smile this morning. :) Funny that not long ago everyone was worried it was £1/litre.

Long live healthy competition, and high street supermarkets for causing the reduction!

BernardBikerchick
12-10-06, 10:11 PM
an hour before 11pm is worth two after 7am :lol: :lol:

wyrdness
13-10-06, 04:36 PM
an hour before 11pm is worth two after 7am :lol: :lol:

An hour of what? Riding? Sex?

therealvw
16-10-06, 05:50 PM
Elvis was the only CIVILIAN, not trained by the FBI to legally carry a sidearm(gun) throughout the United States. Usually gun wearers had to be authorised for each state, or be a fully paid up member of the FBI

TEL
16-10-06, 09:15 PM
TYPEWRITER is the longest word that can be typed using only one row of the keyboard.

The first novel ever written on a typewriter: Tom Sawyer.

northwind
16-10-06, 10:00 PM
Elvis was the only CIVILIAN, not trained by the FBI to legally carry a sidearm(gun) throughout the United States. Usually gun wearers had to be authorised for each state, or be a fully paid up member of the FBI

"That's because he's the King! And you're a schmuck"

therealvw
17-10-06, 06:59 AM
Elvis was the only CIVILIAN, not trained by the FBI to legally carry a sidearm(gun) throughout the United States. Usually gun wearers had to be authorised for each state, or be a fully paid up member of the FBI

"That's because he's the King! And you're a schmuck"
Is that directed at me, or is it a quote!?

Have you seen Bubba Hotep?

philipMac
17-10-06, 02:07 PM
Elvis was the only CIVILIAN, not trained by the FBI to legally carry a sidearm(gun) throughout the United States. Usually gun wearers had to be authorised for each state, or be a fully paid up member of the FBI

"That's because he's the King! And you're a schmuck"
Is that directed at me, or is it a quote!?

Have you seen Bubba Hotep?
That would be a Dogma quote.

He does absolutely hate Mancunians though.

therealvw
18-10-06, 07:53 AM
Elvis was the only CIVILIAN, not trained by the FBI to legally carry a sidearm(gun) throughout the United States. Usually gun wearers had to be authorised for each state, or be a fully paid up member of the FBI

"That's because he's the King! And you're a schmuck"
Is that directed at me, or is it a quote!?

Have you seen Bubba Hotep?
That would be a Dogma quote.

He does absolutely hate Mancunians though.

AHH, Dogma, good film, AND I'm not a MANC. I'm from Lancashire.

BernardBikerchick
19-10-06, 06:38 PM
mount everest is growing an inch every year ! ( this is due to movement of the teutonic plates !) GET ME !!!!

Carsick
19-10-06, 06:43 PM
mount everest is growing an inch every year ! ( this is due to movement of the teutonic plates !) GET ME !!!!
The German plates?

northwind
19-10-06, 06:50 PM
:smt082 So near and yet so far.

BernardBikerchick
19-10-06, 06:53 PM
mount everest is growing an inch every year ! ( this is due to movement of the teutonic plates !) GET ME !!!!
The German plates?

zzrroooooooooooooooooooom !! over me head !!!!!!!! :oops:

lynw
19-10-06, 07:02 PM
mount everest is growing an inch every year ! ( this is due to movement of the teutonic plates !) GET ME !!!!

Tectonic plate theory suggests not only is Everest rising but its moving north Eastwards too. However global warming may actually contribute to its shrinking:

http://news.bbc.co.uk/1/hi/world/asia-pacific/4204539.stm

Everest was measured in 1852 at 29000 feet exactly but was stated as 29002 feet. The calculation was done by trigonometry based on measurements of theodolites taken 150 miles away in India. The 2 extra feet were added on as it was thought the 29000 feet [or 8839 metres] would appear to be an estimate.

The height actually varies depending on the thickness of ice and snow which can be as much as 3.5 metres.

Technically Everest is the highest mountain from sea level. The highest mountain in the world goes to Mauna Kea in Hawaii which is a whacking 10203 metres from sea bed with the mountain attaining 4205 metres above sea level.

The amazing thing is the depth of the earths crust. The mariana trench is so deep you could fit Everest in it [in the Challenger deep] and be covered by 2 Km of water.

Viper
26-10-06, 06:34 AM
Did you know in the novel Frankenstein, the monsters name was ADAM

Baph
27-10-06, 10:11 AM
In the UK:

It's illegal to eat a mince pie on christmas day!

It's also illegal to be drunk on any licenced premesis (bar or pub etc).

It is also illegal to leave baggage unattended, and picking up someone else's lost luggage is an act of terrorism.

Punching someone is an offence that carries a maximum sentence of 5 years.

Until three months ago, you could be sentenced to death in the UK for posting a letter. This is because placing a postage stamp that depicts the reigning monarch, upside down on the envelope, is considered treason. Until 3 months ago, treason was punishable by death!

Dodgeball is illegal in New York, since it's illegal to throw a ball at someone's head for fun.


Happy friday folks!

keithd
27-10-06, 10:14 AM
TYPEWRITER is the longest word that can be typed using only one row of the keyboard.

no its not. this is:-

QTRYQQTETRTTYTYUWQIWRTOPIUYTREWQERTYU

its Polish for "lets go to England"

Filipe M.
27-10-06, 10:41 AM
TYPEWRITER is the longest word that can be typed using only one row of the keyboard.

no its not. this is:-

QTRYQQTETRTTYTYUWQIWRTOPIUYTREWQERTYU

its Polish for "lets go to England"

Looks like Welsh to me... oh forget it, not enough "yy".

Carsick
27-10-06, 10:59 AM
It's also illegal to be drunk on any licenced premesis (bar or pub etc).
I'm fairly sure it's technically illegal to be drunk, full stop.

Jimmy2Feet
27-10-06, 12:22 PM
In the UK:

It's illegal to eat a mince pie on christmas day!

It's also illegal to be drunk on any licenced premesis (bar or pub etc).

It is also illegal to leave baggage unattended, and picking up someone else's lost luggage is an act of terrorism.

Punching someone is an offence that carries a maximum sentence of 5 years.

Until three months ago, you could be sentenced to death in the UK for posting a letter. This is because placing a postage stamp that depicts the reigning monarch, upside down on the envelope, is considered treason. Until 3 months ago, treason was punishable by death!
Dodgeball is illegal in New York, since it's illegal to throw a ball at someone's head for fun.


Happy friday folks!

this is also true for stealing a new forest pony, but what people seem to not realize is that the death penalty was abolished.....well i dont know when, so even if you were to commit "treason" or steal a pony you would only go down for it!!! you life would remain!!
but one thing that you can still get killed for is showing a skull and crossbones flag on a boat/ship whilst at sea, the navy still have the right to blow you out of the water, not that they would but there is nothing stopping them do that at all!!!!


it might also interest you to know that, all you Scotsman out there it is still legal to shoot a Welshman on a sunday(i think) with a longbow!!! cant get done for that.

and whilst on the topic i think it is illegal to feed you cat on a sunday in your front garden in germany, but at the same time it is legal to run down and kill a sausage dog on a sunday in germany!! (i am still not sure whether to believe this one but you never know!!!)

Viper
27-10-06, 12:25 PM
it might also interest you to know that, all you Scotsman out there it is still legal to shoot a Welshman on a sunday(i think) with a longbow!!! cant get done for that.


Any Scotsman fancy a bit of HOVI5 hunting this weekend :lol:

hovis
27-10-06, 12:35 PM
it might also interest you to know that, all you Scotsman out there it is still legal to shoot a Welshman on a sunday(i think) with a longbow!!! cant get done for that.


Any Scotsman fancy a bit of HOVI5 hunting this weekend :lol:

sorry matey, im not welsh :cry:

Viper
27-10-06, 12:36 PM
it might also interest you to know that, all you Scotsman out there it is still legal to shoot a Welshman on a sunday(i think) with a longbow!!! cant get done for that.


Any Scotsman fancy a bit of HOVI5 hunting this weekend :lol:

sorry matey, im not welsh :cry:

You live to fight another day

Baph
27-10-06, 01:09 PM
death penalty was abolished.....well i dont know when
27th September 1999, Jack Straw signed the 6th protocol of the European Convention of Human Rights, this abolished the death penalty.

My previous post relied on information from my boss being accurate. Who can guess the mistake I made there? :lol:

northwind
27-10-06, 06:38 PM
sorry matey, im not welsh :cry:

Luckily, race discrimination laws mean that anything I can do to a Welshman, I can do to anyone else :) Anyone got a longbow? And a book that'll teach me how to shoot a longbow? And possibly some weights, so that I can bulk up enough that I can draw a longbow?

Jimmy2Feet
27-10-06, 06:49 PM
death penalty was abolished.....well i dont know when
27th September 1999, Jack Straw signed the 6th protocol of the European Convention of Human Rights, this abolished the death penalty.

My previous post relied on information from my boss being accurate. Who can guess the mistake I made there? :lol:

is that really true, i thort the death penulty for civiliams was abolished in the 1088's some time!!!! well well you learn something new every day and all that!!! i take it all back!!!

philipMac
27-10-06, 07:18 PM
sorry matey, im not welsh :cry:

Luckily, race discrimination laws mean that anything I can do to a Welshman, I can do to anyone else :) Anyone got a longbow? And a book that'll teach me how to shoot a longbow? And possibly some weights, so that I can bulk up enough that I can draw a longbow?

All this talk brings to mind one of my favorite Bible quotes from JC.

"But those mine enemies, which would not that I should reign over them, bring them hither, and slay them before me."

:smt070 Republican Jesus rules.

lynw
28-10-06, 06:11 PM
is that really true, i thought the death penalty for civilians was abolished in the 1088's some time!!!! well well you learn something new every day and all that!!! i take it all back!!!

The death penalty for "normal" crimes like murder was only abolished in the 1960s.

Razor
31-10-06, 05:11 PM
If all the lego in the world were divided up evenly, we would all get 30 pieces each.

peanut
01-11-06, 08:48 AM
Cool!

I want my lego!

:smt038

Samnooshka
03-11-06, 11:38 AM
Ant trails always fork at 60-degree angles.

Trails leading away from an ant nest always fork at a 60-degree angle, similar to a capital Y. On their way out to pick up food, they take either the left or right branch (30 degrees off their current heading). On their return home, ants need only stay as straight as possible to find their nest.

Law
03-11-06, 12:12 PM
Ant trails always fork at 60-degree angles.

Trails leading away from an ant nest always fork at a 60-degree angle, similar to a capital Y. On their way out to pick up food, they take either the left or right branch (30 degrees off their current heading). On their return home, ants need only stay as straight as possible to find their nest.

:? Really??? That's interesting, time to get my protractor out.

Bear
03-11-06, 01:32 PM
All the fish fingers consumed within the UK last year, if laid end to end, would stretch round the world 7 times.

wyrdness
10-11-06, 09:49 AM
According to cannibals, the tastiest part of a human is the hand.
And according to a robot, hands taste of bacon or ham.
http://www.theinquirer.net/default.aspx?article=35648

Quiff Wichard
10-11-06, 03:55 PM
According to cannibals, the tastiest part of a human is the hand.
And according to a robot, hands taste of bacon or ham.
http://www.theinquirer.net/default.aspx?article=35648


if a cannibal ate a clown-- would he taste funny?

Richie
10-11-06, 04:02 PM
All the fish fingers consumed within the UK last year, if laid end to end, would stretch round the world 7 times.

why would anyone go to this much trouble.... :wink:

lynw
13-11-06, 01:29 PM
One for the skiers on the forum... :wink:

Apparently, one way to save yourself being buried in an avalanche is to make swimming movements.

As per this news article (http://news.bbc.co.uk/2/hi/south_asia/6142632.stm).

:D

YoungMan
16-11-06, 10:46 AM
The one and only time the Inquisition was raised in England was actually in Leeds - to nab the Knights Templars loot.

Just like them Yorkshire folks ain't it?

hovis
16-11-06, 11:36 PM
In 1647 the English Parliament abolished Christmas. :smt114

Stingo
17-11-06, 01:52 PM
At 1352, I listened to Scorpions 'Blackout' on my stereo at work.

Fact.



Not bored or anything. :lol:

BernardBikerchick
21-11-06, 12:24 AM
sharks on average will have about 350 teeth in their mouth at any given time and over their life time they will shed around 27000 teeth ! and I have one in my hand right now !!!!!!!

Viper
21-11-06, 08:58 AM
sharks on average will have about 350 teeth in their mouth at any given time and over their life time they will shed around 27000 teeth ! and I have one in my hand right now !!!!!!!

Put the shark down. It might bite you

Stingo
21-11-06, 09:52 PM
sharks on average will have about 350 teeth in their mouth at any given time and over their life time they will shed around 27000 teeth ! and I have one in my hand right now !!!!!!!

Put the shark down. It might bite you


:smt043 :lol: :lol:

gettin2dizzy
22-11-06, 12:44 AM
sharks on average will have about 350 teeth in their mouth at any given time and over their life time they will shed around 27000 teeth ! and I have one in my hand right now !!!!!!!

Put the shark down. It might bite you


:smt043 :lol: :lol:

a bite mark from a shark will have 350 indentations and require 350 stitches! fact! ;)

lynw
24-11-06, 05:29 AM
Kazakhstan is the worlds ninth largest country, it covers an area about the size of western Europe.

At the present moment, it is snowing in Almaty but unlike the UK, the country hasnt ground to a halt at the first signs of snow. And unlike the UK, no-one speeds in their cars here - guess Darwinism means only cautious and sensible drivers survive. I use those terms in the loosest possible sense regarding lane discipline or the very disctinct lack of it :? :shock:

It is a balmy -16 degrees C in Astana, the capital. I say balmy as its got warmer from yesterday when it was -26 degrees C. :smt103

If you feel like complaining about the weather in the UK, remember it could be worse. :wink: :P :lol: This (http://www.bbc.co.uk/weather/5day.shtml?world=0160) could be your weather forecast for the next five days. :shock: :D

DanDare
24-11-06, 11:07 AM
Kazakhstan is the worlds ninth largest country, it covers an area about the size of western Europe.

At the present moment, it is snowing in Almaty but unlike the UK, the country hasnt ground to a halt at the first signs of snow. And unlike the UK, no-one speeds in their cars here - guess Darwinism means only cautious and sensible drivers survive. I use those terms in the loosest possible sense regarding lane discipline or the very disctinct lack of it :? :shock:

It is a balmy -16 degrees C in Astana, the capital. I say balmy as its got warmer from yesterday when it was -26 degrees C. :smt103

If you feel like complaining about the weather in the UK, remember it could be worse. :wink: :P :lol: This (http://www.bbc.co.uk/weather/5day.shtml?world=0160) could be your weather forecast for the next five days. :shock: :D

My old man spent a few weeks with the Marines in Norway on Exercise.
Whilst there the valley they were staying in was -40c, Health and Safety said this was too cold.

So they moved to the next valley which was -26c which Ok.

What I want to know is when its gets to -10c for me thats pretty cold, how can it get any colder?????????? Bbrrrrrrrrrrr!!!!!!!!

vixis
27-11-06, 11:11 PM
the only trivia I can think of is that the word "do" in the English language is an etymological mystery - everyone knows what it does, no one knows where it comes from and it usually take a good two pages in any good thesaurus to explain the word...god, I need to get my CBT so I can get out more...!

philipMac
27-11-06, 11:15 PM
the only trivia I can think of is that the word "do" in the English language is an etymological mystery - everyone knows what it does, no one knows where it comes from and it usually take a good two pages in any good thesaurus to explain the word...god, I need to get my CBT so I can get out more...!

Yeah, and "do" doesn't have an equivalent in a lot of languages. So, teaching it to people who have never used it or an analogue of it, and don't even understand why its needed can be a bugger.

Or so I am told. :roll:

lynw
28-11-06, 08:11 AM
What I want to know is when its gets to -10c for me thats pretty cold, how can it get any colder?????????? Bbrrrrrrrrrrr!!!!!!!!

Tbh, -10 is ok ie its bearable if youre wrapped up properly.

I walked to the restaurant 5 mins from my hotel last night and I arrived with white "mascara". In what was -30 degrees my eyelashes started to freeze as were my eyeballs. :shock:

Interesting post on the word "do".

Russian is a language which doesnt have the concept of saying "I am" or "they are" or "it is" - a fact I would have loved to know at school when learning French verbs.... :P :lol: It is a very literal languange - Ya Angleechenka is literally I English meaning I am English. :D

Baph
05-12-06, 11:36 AM
There are now more than 100 million websites on the internet!

I'm also bored, so I might start to catalogue them all!

Baph
05-12-06, 11:56 AM
There are more than 10^16 prokaryotes (typically bacteria) in a ton of soil -- there are only 10^11 stars in our galaxy!

And I'm still bored.... :lol:

There are 5 million more women than men in America! The US is 49.1% male and 50.9% female. I'm emmigrating! :D

Filipe M.
05-12-06, 11:57 AM
And I'm still a bored eukaryote.... :lol:

Baph
05-12-06, 11:59 AM
And I'm still a bored eukaryote.... :lol:
Ah, but I'm a eukaryote of the protist genus. yet another interesting fact... damn I'm good today :D

Filipe M.
05-12-06, 12:07 PM
And I'm still a bored eukaryote.... :lol:
Ah, but I'm a eukaryote of the protist genus. yet another interesting fact... damn I'm good today :D

So should we call you Amoeba from now on? :?

Alpinestarhero
05-12-06, 12:24 PM
And I'm still a bored eukaryote.... :lol:
Ah, but I'm a eukaryote of the protist genus. yet another interesting fact... damn I'm good today :D

So should we call you Amoeba from now on? :?

He's not a single cell organism...

...I hope :?

I should be teeming with interesting facts, but i cant think of any.

Oh yes! Light can behave like a particle, aswell as a wave. So can electrons. Infact, there are studies which suggest even atoms have this wave particle duality...

Matt

Alpinestarhero
14-12-06, 06:50 PM
Plastics can conduct electricity!

Matt

Spiderman
14-12-06, 08:26 PM
Plastics can conduct electricity!

Matt

this thread is becoming a bit like that program QI. The more things i read here that are interesting or amazing and that i didnt know, the more the chance that someone will post some total garbage and not even be challenged about it.

So for this reason only, I say to you Sir.... PROVE IT!!!!!!

Carsick
14-12-06, 08:34 PM
^ http://en.wikipedia.org/wiki/Conductive_polymer

Spiderman
14-12-06, 08:48 PM
Thanks Mike.... BUT it says.. A conductive polymer is an organic polymer semiconductor, or an organic semiconductor. and surley if somethings "organic" then by definition its not just a "plastic" that is man made??

Wish i hadnt asked now. lol

Carsick
14-12-06, 09:32 PM
^ In chemistry, organic means a compound containing carbon and hydrogen. It has nothing to do with how it was created.

All plastics are organic.

philipMac
15-12-06, 12:18 AM
OH SNAP!



Spidey. You just got pwnd. Sorry to break the news mate.

philipMac
15-12-06, 12:23 AM
I better post up a fact then.

Right. Driving through the Lincoln tunnel, at 60 mph, while somebody leans out the window, reefing their guts up a) leaves interesting patterns on your car, and
b) provokes some ire in the driver of the following car. (Said car also obtains interesting patterns on his bonnet.)

Alpinestarhero
15-12-06, 09:17 AM
Plastics can conduct electricity!

Matt

this thread is becoming a bit like that program QI. The more things i read here that are interesting or amazing and that i didnt know, the more the chance that someone will post some total garbage and not even be challenged about it.

So for this reason only, I say to you Sir.... PROVE IT!!!!!!

I have an extensive report that i wrote and some literature papers if you would like them...

And i can expalin how it works quite esily (i did have to work it out for myself after all :shock:)

Matt

philipMac
15-12-06, 05:34 PM
I have an extensive report that i wrote and some literature papers if you would like them...

And i can expalin how it works quite esily (i did have to work it out for myself after all :shock:)

Matt

Pfft. Go away out of here with your Lit searches. At the org we are only interested in talking to the original authors.


Of Nature papers. :wink:


OK. Speaking of Nature papers. Ahem. In the last few years, a completely new way of controlling genes in plants and animals was discovered, that fundamentally changed the feed-forward paradigm of DNA->mRNA->Protein.

This DNA->mRNA->Protein concept has been so central to Biology that when I was doing my degree, a few years ago, it was still being taught as "The Central Paradigm" of biology.

Yet, a couple of years later, its known that this is not the case.

Interesting how we think how great we are at science, and then we discover we didnt notice something totally fundamental for years.

Alpinestarhero
15-12-06, 05:48 PM
Really? How is it all thought to work now then?

My literature search will be the basis of my very own research to be undertaken next year (my final year) :D I'm dead excited, and I have a few ideas.

As for Nature...its only for people who want to boost their rating, get as many people as possible to read their work :P Na, only joking. I would love to get a paper published in Nature, its a very prestigious journal. I would especially like a paper published in Nature Materials :D Maybe one day...

Matt

philipMac
15-12-06, 07:08 PM
Really? How is it all thought to work now then?

My literature search will be the basis of my very own research to be undertaken next year (my final year) :D I'm dead excited, and I have a few ideas.

As for Nature...its only for people who want to boost their rating, get as many people as possible to read their work :P Na, only joking. I would love to get a paper published in Nature, its a very prestigious journal. I would especially like a paper published in Nature Materials :D Maybe one day...

Matt

Well, the DNA->mRNA->Protein idea still works, but its only part of the story.
Another part, we still dont know how much but it seems like a fair bit at least, involves this DNA->mRNA->DNA path.

So, these small miRNAs (microRNAs) are not being transcribed into proteins, they are looping straight back, and deciding how and what other genes are being transcribed.

Parts of these pathways can be used to short circuit endogenous genes in animals, so you can "trick" them into knocking down one of their own specific genes without creating a mutant. (Mutant generation is a pain.) This is called RNA interference. The two dudes that discovered this got the Nobel prize this year.

I got one in Nature Genetics last year. It's cool. They send you free journals from then on, cause you are an "Esteemed scientist" :lol:

Alpinestarhero
15-12-06, 07:51 PM
Ah, thats cool. I thought there was something missing when I got taught how proteins are made in the body (made as in figured out from the DNA, you get me i hope)

Have you got the name(s) of the people who did the work to find this out? Its interesting!

What do you do for a living, may I ask?

Matt

philipMac
15-12-06, 08:44 PM
Ah, thats cool. I thought there was something missing when I got taught how proteins are made in the body (made as in figured out from the DNA, you get me i hope)

Have you got the name(s) of the people who did the work to find this out? Its interesting!

What do you do for a living, may I ask?

Matt

Names of the people who noticed RNAi interference are Andy Fire and Craig Mello. You will see Fire et al on basically every RNAi paper out there.
Name of the miRNAi people.. emm, well, people were working on them before they realised what they were. They thought they were ordinary genes. They noticed that they had very pleiotropic effects. So, I suppose all those people who werked on those Pasha and Drosha prots.

I am a research scientist. According to my visa :) Em, I suppose I am a bioinformatician / genetics data miner specifically.

To find out more, funnily enough the guy that sits next to me, wrote a review article for Nature Genetics this month on it. Its good. You can look through that and look at the papers Kevin reffed out if you are curious.

http://www.nature.com/ng/journal/v38/n12/abs/ng1910.html

Alpinestarhero
16-12-06, 08:22 PM
Thanks for that! I'll have a read in my spare time.

Matt

Baph
19-12-06, 09:20 AM
V-Wipes are excellent at removing ice from your seat!

FACT!

Alpinestarhero
19-12-06, 09:47 AM
Hehe :D

I saw the frost on my dads car today, and felt the chill of the fog (fog is a colloid; the dispersed phase is water (liquid), the dispersion medium is air (gas). Theres my interesting fact), Decided that today isnt a good day to go learning more about my SV and extending my riding limits, so I'm going to revise for my exams instead. Or at least looook like I am and post on here.

Matt

Baph
19-12-06, 09:58 AM
Decided that today isnt a good day to go learning more about my SV and extending my riding limits

Limits and knowledge can only be expanded by testing both. FACT!

(I had to ride home last night in freezing fog, so I knew what the weather would be like this morning, so doubled my commute time today & took it REALLY easy. Luckily I work for someone that if I decide it's too dangerous to ride, they don't mind me "working" from home.)

Menai bridge looks COOL when all you can see around you is blue haze. FACT!

zobo
20-12-06, 05:42 PM
:shock: :shock: By 2040 the Arctic Ocean will be largely ice-free in the summer...!!! :shock: :shock:

hovis
20-12-06, 06:53 PM
The doctor said I wouldn't have so many nose bleeds if I kept my finger outta there.
:smt116

zobo
20-12-06, 07:13 PM
sprouts make you f@rt.. sorry I couldn't help myself :-#

Alpinestarhero
23-12-06, 07:40 PM
Decided that today isnt a good day to go learning more about my SV and extending my riding limits

Limits and knowledge can only be expanded by testing both. FACT!

(I had to ride home last night in freezing fog, so I knew what the weather would be like this morning, so doubled my commute time today & took it REALLY easy. Luckily I work for someone that if I decide it's too dangerous to ride, they don't mind me "working" from home.)

Menai bridge looks COOL when all you can see around you is blue haze. FACT!

LOL thats true; i managed to get out the other day and expand my limits and knowledge. First smooth slide from the front on the greasy roads. Well, it felt like a slide to me, or some sort of drifty feeling. Anywho, it wasnt horrible. The SV really is a confidence-inspiring machine.

Oh, todays Fact Of The Day: Water can be used as a fuel, apparently. I dont know how. But it can.





Um



Not.

Matt

Alpinestarhero
23-12-06, 07:45 PM
The doctor said I wouldn't have so many nose bleeds if I kept my finger outta there.
:smt116

I was told that by a freind, but I just cant help myself :(

Matt

Alpinestarhero
24-12-06, 08:11 PM
The smell of poop comes from a chemical called Skatole. However, in very low concentrations, this molecule smells sweet...

More info here:

http://www.chm.bris.ac.uk/motm/motm.htm

Matt

philipMac
24-12-06, 10:26 PM
There are a few orders of magnitude more genes in humans that are to do with out sense of smell, than our vision.

Interesting... since our vision is decent, and our sense of smell is rubbish.

tinpants
03-01-07, 06:54 PM
Contrary to popular belief, masturbation does not make you blind. :toss: :-dd




Now, where did I put those glasses?................. :shock: :lol:

netsurfer
03-01-07, 07:41 PM
The smell of poop comes from a chemical called Skatole. However, in very low concentrations, this molecule smells sweet...


And butyric acid, a chemical that gives vomit its smell is also in parmesan cheese, hence the stench.

Pete

Alpinestarhero
03-01-07, 08:43 PM
I deteste parmasan.

There's two schools of thought knocking around as to how we smell. One school of thought is the "lock and key" idea; the substrate (the smelly chemical) binds to the receptor (in your nose) and if it fits correctly, it gives off a particular smell.

The other school of thought (and my prefered idea) is that the vibrations of the substrate (caused by bonds stretching and bending etc etc) and the subsequent distortions of the receptors electron field (cant put it any better way) cause the smell thats...smelt.

And netsurfer, lets be IUPAC about this...it also goes by the name of Butanoic acid :)

Acids smell worse with increasing chain length. Anyone ever caught a wiff of octanol?


Matt

DanDare
04-01-07, 04:55 PM
The name 'Tank' given to the armoured military vehicle was derived from the British during the First World War. To deter spies in England the parts to build it where listed as being for giant water tanks on the paperwork. Later the parts were assembled in secret and called........a Tank.

Boring I know, but its the best I got! :roll: :cry:

hovis
07-01-07, 07:21 PM
Canada exports more cabbage to the USA than the rest of the world combined.

The Basket
07-01-07, 07:45 PM
Life Expectancy in medieval England was about 30 years old!

The Black Death (1340's)was supposed to have killed a third of the British Isles population.

The 21st Century don't seem so bad now.